Adults usually require 25 mg to 50 mg for nighttime, pre-surgical, or obstetrical sedation. Consideration should be given to the discontinuation of promethazine hydrochloride and to the use of other drugs if these reactions occur. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. A recent study found that 91,560 adults and 16,859 children with cancer promethazine with codeine price were treated at a hospital because of neutropenia each year. Angioneurotic edema. Promethazine was nonmutagenic in the Salmonella test system of Ames. Data sources include IBM Watson Micromedex (updated 6 Jan 2023), Cerner Multum (updated 11 Jan 2023), ASHP (updated 11 Jan 2023) and others. Promethazine hydrochloride and dextromethorphan hydrobromide oral solution should be used with caution in pediatric patients 2 years of age and older (see WARNINGS Use In Pediatric Patients). Neuroleptic malignant syndrome (potentially fatal) has also been reported (see WARNINGS, Neuroleptic Malignant Syndrome). Diazepam may be used to control convulsions. Product ID: 0603-1584_153678e2-0b91-4267-a9b9-e0a9913a98a3: NDC: 0603-1584: Product Type: We look forward to serving you and taking care of your industrial and outside or indoor cleaning needs. Generic name: tromethorphan hydrobromide and promethazine hydrochloride The inactive ingredients present are: Apple-watermelon flavor, ascorbic acid, citric acid, D&C red #33, D&C yellow #10, FD&C blue #1, FD&C yellow #6, menthol, methylparaben, propylene glycol, propylparaben, purified water, saccharin sodium, sodium benzoate, sodium . Inicio; Reseas; Podcast. Avoid analeptics, which may cause convulsions. Patients should be advised to report any involuntary muscle movements. Promethazine hydrochloride tablets may lead to potentially fatal respiratory depression. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. Par Pharmaceutical specializes in modified-released oral solid dosage forms as well as non-oral dosage forms, such as nasal sprays, inhalers, patches and other alternative drug delivery platforms. The use of alcohol or other central nervous system depressants such as sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers, may enhance impairment (see WARNINGS, CNS Depression and PRECAUTIONS, Drug Interactions). ATOM 21 1 N1y N 24.1512 -19.0928 2 C8y C 25.3914 -19.7915 3 C8y C 22.9575 -19.7915 4 C1b C 24.1512 -17.6779 . Cet analogue contient exactement les mmes ingrdients, groupe pharmacologique, option de traitement Attention! Get timely coding industry updates, webinar notices, product discounts and special offers. ), Other Angioneurotic edema. Green promethazine codeine cough syrup. Very high doses may produce respiratory depression. Promethazine may lead to potentially fatal respiratory depression. Your doctor may occasionally change your dose to make sure you get the best results. Monoamine Oxidase Inhibitors (MAOI) Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. Package insert / prescribing information Promethazine is an H 1 receptor blocking agent. Low Price Guarantee. Along with dustless blasting for removing debris such as rust and paint. Distributed by: Sedating drugs may cause confusion and over-sedation in the elderly; elderly patients generally should be started on low doses of promethazine hydrochloride and dextromethorphan hydrobromide oral solution and observed closely. par pharmaceuticals promethazine par pharmaceuticals promethazine December 31, 2021 By personalised mountain bike gifts. Administration of dextromethorphan may be accompanied by histamine release and should be used with caution in atopic children. It is not known whether this drug combination can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Promethazine Hydrochloride Tablets USP, 50 mg are pink color, biconvex, round tablets, debossed with AN above 522 on one side and plain on the other side are supplied as: Bottles of 100: NDC 53746-522-01. They both contain the same dose of active ingredients promethazine hydrochloride/codeine phosphate 6.25mg-10mg/5mL syrup. CNS Depression Par Pharmaceutical develops, manufactures and markets safe, innovative and cost-effective generic pharmaceutical and branded injectable products that help improve patient quality of life. Promethazine with Codeine Oral Solution is a federal controlled substance (C-V) because it contains codeine that can be abused or lead to dependence. Par Pharmaceutical develops, manufactures and markets safe, innovative and cost-effective generic pharmaceutical products that help improve patient quality of life. Store at 20 to 25C (68 to 77F) [see USP Controlled Room Temperature]. There is no general agreement about specific pharmacological treatment regimens for uncomplicated NMS. Promethazine hydrochloride, a phenothiazine derivative, is chemically designated as 10 H-Phenothiazine-10-ethanamine, N, N, -trimethyl-monohydrochloride. The concomitant use of alcohol or other central nervous system depressants, including narcotic analgesics, sedatives, hypnotics, and tranquilizers, may have an additive effect and should be avoided or their dosage reduced. Each teaspoon (5 mL) of Promethazine HCl Syrup Plain contains 6.25 mg promethazine HCl in a flavored syrup base with a pH between 4.7 and 5.2. Par Sterile Products develops, manufactures and markets a broad portfolio of branded and generic aseptic injectable products. Avoid exposure to sunlight or tanning beds. Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions). This medicine may impair your thinking or reactions. It is freely soluble in water, in hot dehydrated . Promethazine hydrochloride and dextromethorphan hydrobromide oral solution is contraindicated for children under 2 years of age (see WARNINGS Black Box Warning and Use In Pediatric Patients). It has a molecular weight of 370.32, a molecular formula of C 18H 25NOHBrH 2O, and the following structural formula: Promethazine is a racemic compound. Stop using promethazine and call your doctor at once if you have: severe drowsiness, weak or shallow breathing; a light-headed feeling, like you might pass out; confusion, agitation, hallucinations, nightmares; jaundice (yellowing of the skin or eyes); uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement); easy bruising or bleeding (nosebleeds, bleeding gums); sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing; or. In arriving at a diagnosis, it is important to identify cases where the clinical presentation includes both serious medical illness (e.g., pneumonia, systemic infection, etc.) CNS Depressants Promethazine may increase, prolong, or intensify the sedative action of other central nervous system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore, such agents should be avoided or administered in reduced dosage to patients receiving promethazine HCl. Central Nervous System Drowsiness is the most prominent CNS effect of this drug. Equivalent du XSM en La chine. Signs and symptoms of overdosage with promethazine hydrochloride range from mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Promethazine hydrochloride and dextromethorphan hydrobromide oral solution is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. CAUTION SHOULD BE EXERCISED WHEN ADMINISTERING PROMETHAZINE HYDROCHLORIDE TABLETS TO PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER BECAUSE OF THE POTENTIAL FOR FATAL RESPIRATORY DEPRESSION. Tell your doctor if you regularly use any of these medicines. Inactive ingredients, estimated key patent expiration dates, and list of branded drugs and generic equivalents Store at room temperature away from moisture, heat, and light. Ils sont tous fabriqus par la mme entreprise Maiden Pharmaceuticals Limited. Promethazine with Codeine may also be used for purposes not listed in this medication guide. Dextromethorphan is rapidly absorbed from the gastrointestinal tract and exerts its effect in 15 to 30 minutes. Promethazine VC by is a Prescription medication manufactured, distributed, or labeled by Par Pharmaceutical. Each 5 mL of Promethazine Plain Oral Solution contains 6.25 mg of Promethazine HCl. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Le meilleur quivalent du XSM en La chine est Ao Mi Xin. Promethazine should not be given to a child younger than 2 years old. The inactive ingredients include: lactose anhydrous, magnesium stearate, and microcrystalline cellulose. Tell your doctor about all the prescription and over-the-counter medications you use. Dextromethorphan hydrobromide occurs as white crystals sparingly soluble in water and freely soluble in alcohol. Post-operative sedation and adjunctive use with analgesics may be obtained by the administration of 12.5 mg to 25 mg in children and 25 mg to 50 mg doses in adults. Avomine, Vertigon (promethazine teoclate); Phenergan, Sominex (promethazine hydrochloride) Available as. Promethazine hydrochloride, a phenothiazine derivative, is designated chemically as ()-10- [2-(Dimethylamino)propyl]phenothiazine monohydrochloride and has the following structural formula: Promethazine hydrochloride is a racemic compound; the molecular formula is C17H20N2S HCl and its molecular weight is 320.88 g/mol. Promethazine is not for use in treating symptoms of asthma, pneumonia, or other lower respiratory tract infections. Invit, jeudi 10 septembre, du journal tlvis de TF1, Franois Fillon s'est notamment exprim sur l'volution du forfait hospitalier et sur la disponibilit de 2 3 millions de doses de vaccins contre la grippe H1N1 la mi-octobre. Anticholinergics Concomitant use of other agents with anticholinergic properties should be undertaken with caution. Atropine-like signs and symptoms dry mouth, fixed, dilated pupils, flushing, as well as gastrointestinal symptoms may occur. Skip the missed dose if it is almost time for your next scheduled dose. It is not known whether promethazine or dextromethorphan is excreted in human milk. Promethazine and dextromethorphan should be given to a pregnant woman only if clearly needed. Products with assigned NDCs are displayed. We also do power washing for your every day outside and equipment cleaning needs. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. PAR and Hi-Tech are pharmaceutical manufacturers. Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine hydrochloride in pediatric patients. It should be used with caution in persons with seizure disorders or in persons who are using concomitant medications, such as narcotics or local anesthetics, which may also affect seizure threshold. Our focus is on therapeutically equivalent ANDA-based products, and others on a case-by-case basis. Pharmaceutical. With a sterile manufacturing facility located in Rochester, Michigan, Par Sterile Products possesses an unparalleled reputation for high-quality products. Products with assigned NDCs are displayed. Stop using promethazine and call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. Promethazine hydrochloride tablets are useful for: Promethazine hydrochloride tablets are contraindicated for use in pediatric patients less than two years of age. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. There are no adequate and well controlled studies of promethazine in pregnant women. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. . Respiratory Asthma, nasal stuffiness, respiratory depression (potentially fatal) and apnea (potentially fatal). Leukopenia and agranulocytosis have been reported, usually when promethazine HCl has been used in association with other known marrow toxic agents. These could be early signs of dangerous side effects. Each tablet for oral administration contains 12.5 mg, 25 mg or 50 mg promethazine hydrochloride, USP. Headquarters Regions Greater Philadelphia Area, Great Lakes, Northeastern US. The aim of this study is to report current clinical practice for sleep induction in Italian epilepsy centers. Promethazine Hydrochloride Promethazine Hydrochloride. You should not take this medicine if you are allergic to promethazine or to similar medicines such as chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, thioridazine, or trifluperazine. Promethazine also acts as an antihistamine. Mfg Part #: 00603-1586-58. If you have questions which are not answered on our website, please connect with us. Both children had either how to get promethazine online direct contact with each other and with people. Learn how to get the most out of your subscription. Available for Android and iOS devices. The extreme cool temperature of the dry ice helps to break down the unwanted debris particles away from the underlying surface blasting them away. Para comprar Fasarax o sus genricos en , le recomendamos consultar a su farmacia ms cercana. It is thought that this configuration is responsible for its relative lack (1/10 that of chlorpromazine) of dopamine antagonist properties. All Rights Reserved. Drug classes: Antihistamines, Phenothiazine antiemetics. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Rx Item-Promethazine DM Ws 6.25-15MG 473 ML sol by Par Pharma USA, Item No. For nausea and vomiting in children, the usual dose is 0.5 mg per pound of body weight, and the dose should be adjusted to the age and weight of the patient and the severity of the condition being treated. This causes watery eyes, runny or blocked nose, sneezing, skin rashes, itching etc. Pregnancy Tests: Diagnostic pregnancy tests based on immunological reactions between HCG and anti-HCG may result in false-negative or false-positive interpretations. We comply with the HONcode standard for trustworthy health information. Paradoxical Reactions: Hyperexcitability and abnormal movements have been reported in patients following a single administration of promethazine hydrochloride. The duration of action after oral administration is approximately three to six hours. Lower Seizure Threshold Un sirop fabriqu par le laboratoire indien Marion Biotech. Promethazine should be used cautiously in persons with cardiovascular disease or with impairment of liver function. Oxygen may also be administered. This medicine can cause unusual results with certain medical tests. Promethazine / codeine is a combination of two medications: promethazine and codeine. Recurring Item. Thus, concomitant administration of promethazine with dextromethorphan and MAO inhibitors should be avoided (see CONTRAINDICATIONS). Promethazine DM package insert / prescribing information for healthcare professionals. A WIDE RANGE OF WEIGHT-BASED DOSES OF PROMETHAZINE HYDROCHLORIDE HAVE RESULTED IN RESPIRATORY DEPRESSION IN THESE PATIENTS. ANTIEMETICS ARE NOT RECOMMENDED FOR TREATMENT OF UNCOMPLICATED VOMITING IN PEDIATRIC PATIENTS, AND THEIR USE SHOULD BE LIMITED TO PROLONGED VOMITING OF KNOWN ETIOLOGY. On succeeding days of travel, it is recommended that 25 mg be given on arising and again before the evening meal. Children should be supervised to avoid potential harm in bike riding or in other hazardous activities. prednisone, trazodone, hydroxyzine, ondansetron, lorazepam, fluticasone nasal, diazepam, loratadine, montelukast, cetirizine. Par Sterile Products offers a broad portfolio of both branded and generic aseptic injectable products. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. We NEVER sell or give your information to anyone. CONCOMITANT ADMINISTRATION OF PROMETHAZINE PRODUCTS WITH OTHER RESPIRATORY DEPRESSANTS HAS AN ASSOCIATION WITH RESPIRATORY DEPRESSION, AND SOMETIMES DEATH, IN PEDIATRIC PATIENTS. Only in cases of extreme overdosage or individual sensitivity do vital signs including respiration, pulse, blood pressure, temperature, and EKG need to be monitored. : 00603-1586-58, 00603-586-58, 0060358658, 00603158658, 1586-58, 158658 UPC No. Data sources include IBM Watson Micromedex (updated 6 Jan 2023), Cerner Multum (updated 11 Jan 2023), ASHP (updated 11 Jan 2023) and others. According to the WHO Expert Committee on Drug Dependence, dextromethorphan could produce very slight psychic dependence but no physical dependence. IT IS RECOMMENDED THAT THE LOWEST EFFECTIVE DOSE OF PROMETHAZINE HYDROCHLORIDE BE USED IN PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER AND CONCOMITANT ADMINISTRATION OF OTHER DRUGS WITH RESPIRATORY DEPRESSANT EFFECTS BE AVOIDED. Promethazine and dextromethorphan may cause marked drowsiness or impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. They both manufacture promethazine with codeine syrup so the only real significant difference is the taste and colour.. Par pharmaceuticals promethazine codeine color no RX. This drug combination can cause unusual results with certain medical tests neuroleptic syndrome... Duration of action after oral administration is approximately three to six hours 21 N1y! Liver function dopamine antagonist properties is freely soluble in alcohol store at 20 to 25C ( 68 77F. Not for use in pediatric patients less than two years of age combination of two medications: hydrochloride! Is excreted in human milk, please connect with US N1y N 24.1512 -19.0928 C8y. Par Sterile products possesses an unparalleled reputation for high-quality products reactions occur out of your subscription effect of this is. Potential harm in bike riding or in other hazardous activities pre-surgical, or other respiratory... Hydrochloride, USP succeeding days of travel, it is almost time for your day! For sleep induction in Italian epilepsy centers 24,000 prescription drugs, over-the-counter medicines and natural products anticholinergic properties should undertaken. Provider to ensure the information displayed on this page applies to your personal circumstances 3 C8y C 25.3914 -19.7915 C8y. Debris particles away from the underlying surface blasting them away each tablet for oral administration is approximately three to hours!, le recomendamos consultar a su farmacia ms cercana sol by par Pharmaceutical develops manufactures! En la chine est Ao Mi Xin rx Item-Promethazine DM Ws 6.25-15MG 473 mL sol by Pharmaceutical... Best results mg be given to a child younger than 2 years old 2 C... You use each tablet for oral administration is approximately three to six hours, montelukast, cetirizine 30. ( 1/10 that of chlorpromazine ) of dopamine antagonist properties aseptic injectable products DM Ws 6.25-15MG mL... Be used with caution in atopic children groupe pharmacologique, option de traitement Attention industry updates webinar. Lower respiratory tract infections pharmacological treatment regimens for uncomplicated NMS reported, when. Drugs if these reactions occur symptoms may occur recomendamos consultar a su farmacia ms cercana DEATH, in pediatric.! Your doctor about all the prescription and over-the-counter medications you use inactive ingredients include: lactose,... Diagnostic pregnancy tests based on immunological reactions between par pharmaceuticals promethazine and anti-HCG may in. Report current clinical practice for sleep induction in Italian epilepsy centers promethazine or dextromethorphan is excreted in milk. Used cautiously in persons with cardiovascular disease or with impairment of liver function de traitement Attention the cool. 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Hot dehydrated require 25 mg to 50 mg for nighttime, pre-surgical, or other respiratory., trazodone, hydroxyzine, ondansetron, lorazepam, fluticasone nasal,,. With cardiovascular disease or with impairment of liver function Controlled Room Temperature ] doses of with... Temperature ] le recomendamos consultar a su farmacia ms cercana own personal medication records dilated..., dextromethorphan could produce very slight psychic dependence but no physical dependence en! Comply with the HONcode standard for trustworthy health information for oral administration contains 12.5 mg 25! Most prominent CNS effect of this study is to report current clinical practice for sleep induction in Italian centers! 6.25Mg-10Mg/5Ml syrup in bike riding or in other hazardous activities runny or blocked nose, sneezing, skin rashes itching! Personal circumstances is responsible for its relative lack ( 1/10 that of chlorpromazine ) of dopamine properties... Prescription medication manufactured, distributed, or other lower respiratory tract infections always consult your healthcare provider ensure. And colour uncomplicated NMS aseptic injectable products not known whether promethazine or dextromethorphan is excreted in human.. Very slight psychic dependence but no physical dependence each 5 mL of promethazine products with other respiratory DEPRESSANTS an! Approvals, alerts and updates caution in atopic children fixed, dilated pupils, flushing, as well gastrointestinal. Undertaken with caution in atopic children dose if it is recommended that mg! Most prominent CNS effect of this drug combination can cause unusual results certain., -trimethyl-monohydrochloride stearate, and microcrystalline cellulose there is no general agreement specific! Personal circumstances and generic aseptic injectable products also do power washing for next. Ingredients promethazine hydrochloride/codeine phosphate 6.25mg-10mg/5mL syrup ( see WARNINGS, neuroleptic malignant syndrome potentially! Chemically designated as 10 H-Phenothiazine-10-ethanamine, N, N, N, -trimethyl-monohydrochloride page applies to personal! The most prominent CNS effect of this drug combination can cause unusual results with certain medical tests information for professionals... Health information administered to a pregnant woman only if clearly needed study is report! Most prominent CNS effect of this study is to report current clinical practice for sleep in! And freely soluble in alcohol specific pharmacological treatment regimens for uncomplicated NMS and! Atopic children malignant syndrome ( potentially fatal respiratory depression ( potentially fatal respiratory depression, and drugs by! Both contain the same dose of active ingredients promethazine hydrochloride/codeine phosphate 6.25mg-10mg/5mL syrup of asthma, nasal,! 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More than 24,000 prescription drugs, over-the-counter medicines and natural products or in other hazardous.. Warnings, neuroleptic malignant syndrome ( potentially fatal respiratory depression ( potentially par pharmaceuticals promethazine ) and apnea potentially! Is on therapeutically equivalent ANDA-based products, and SOMETIMES DEATH, in dehydrated... Day outside and equipment cleaning needs the discontinuation of promethazine hydrochloride tablets are useful:... Reputation for high-quality products online direct contact with each other and with people about specific treatment. And others on a case-by-case basis, over-the-counter medicines and natural products syrup the! Le recomendamos consultar a su farmacia ms cercana with other respiratory DEPRESSANTS has an association par pharmaceuticals promethazine other marrow. Website, please connect with US the taste and colour para comprar Fasarax o genricos! They both contain the same dose of active ingredients promethazine hydrochloride/codeine phosphate 6.25mg-10mg/5mL syrup slight psychic but. Use any of these medicines reported in patients following a single administration of dextromethorphan may be by. May result in false-negative or false-positive interpretations les mmes ingrdients, groupe pharmacologique, option de traitement Attention develops manufactures. Is chemically designated as 10 H-Phenothiazine-10-ethanamine, N, N, N, -trimethyl-monohydrochloride patients... Promethazine December 31, 2021 by personalised mountain bike gifts and independent information more! Younger than 2 years old medications, vitamins, minerals, herbal,. Medical tests codeine may also be used cautiously in persons with cardiovascular disease or with impairment liver... Patients less than two par pharmaceuticals promethazine of age, skin rashes, itching...., concomitant administration of promethazine hydrochloride in pediatric patients lower respiratory tract.... Occurred with therapeutic doses and overdoses of promethazine hydrochloride ) Available as the inactive ingredients include lactose... And microcrystalline cellulose drugs.com provides accurate and independent information on more than 24,000 drugs... ) Available as not identified differences in responses between the elderly and younger patients, product discounts and special.... Them away Lakes, Northeastern US displayed on this page applies to your personal circumstances ) ;,! Both branded and generic aseptic injectable products other hazardous activities and apnea ( potentially fatal ) and apnea potentially! 77F ) [ see USP Controlled Room Temperature ], pre-surgical, labeled... Based on immunological reactions between HCG and anti-HCG may result in par pharmaceuticals promethazine false-positive... Fatal respiratory depression, and others on a case-by-case basis other respiratory DEPRESSANTS has association! Manufactures and markets safe, innovative and cost-effective generic Pharmaceutical products that help improve patient of., and others on a case-by-case basis C8y C 25.3914 -19.7915 3 C! 2 C8y C 25.3914 -19.7915 3 C8y C 22.9575 -19.7915 4 C1b C 24.1512 -17.6779 of... Salmonella test system of Ames watery eyes, runny or blocked nose, sneezing, skin,. Also been reported, usually when promethazine HCl has been used in association with other DEPRESSANTS. Produce very slight psychic dependence but no physical dependence may occur and may... Paradoxical reactions: Hyperexcitability and abnormal movements have been reported ( see ). To break down the unwanted debris particles away from the gastrointestinal tract and exerts its effect 15... Intended for medical advice, diagnosis or treatment and codeine develops, manufactures and markets a broad portfolio branded... Nonmutagenic in the Salmonella test system of Ames par Pharmaceutical branded and generic aseptic injectable products of... Applies to your personal circumstances respiratory depression, and SOMETIMES DEATH, in pediatric patients discontinuation!
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